Bioavailability of pharmaceuticals in Northern Pike in the St. Lawrence River
Aquatic systems near major urban centers are constantly contaminated with effluent from wastewater treatment plants (WWTP). Pharmaceuticals are part of the contamination and several classes of drugs have been detected in surface waters in the last decade. To better understand the impact of those pharmaceuticals in ecosystems, the exposure to aquatic species needs to be investigated. This study presents a new simple and rugged quantitative method for the determination of several classes of drugs using plasma from Northern Pike (Esox lucius) environmentally exposed to a major but highly diluted urban effluent. The concentration of six common drugs (diclofenac, ibuprofen, naproxen, salbutamol, sulfamethoxazole and trimethoprim) and one major metabolite (2-hydroxy-ibuprofen) are shown in this dataset.
Scientific Publication - Determination of the bioavailability of selected pharmaceutical residues in fish plasma using liquid chromatography coupled to tandem mass spectrometry
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