Cumulative effects of municipal effluent and parasite infection in yellow perch

Cumulative effects of municipal effluent and parasite infection in yellow perchMultiple metabolic, immune and reproductive effects have been reported in fish residing in effluent-impacted sites. Natural stressors such as parasites also have been shown to impact the responses of organisms to chronic exposure to municipal effluent in the St. Lawrence River (Quebec, Canada). In order to comprehensively evaluate the cumulative impacts of anthropogenic and natural stressors on the health of yellow perch, differential mRNA transcription profiles were examined in juvenile females collected from effluent-impacted and upstream sites with low or high infection levels of the larval trematode Apophallus brevis. Transcriptomics was used to identify biological pathways associated with environmental exposure. Overall, results indicated that juvenile yellow perch responded strongly to combined parasite and effluent exposure, suggesting cumulative effects on immune responses, inflammation and lipid metabolism mediated by retinoid receptors. The present study highlight the importance of using a comprehensive approach combining transcriptomics and endpoints measured at higher levels of biological organization to better understand cumulative risks of contaminants and pathogens in aquatic ecosystems.

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Scientific Publication - Cumulative effects of municipal effluent and parasite infection in yellow perch: A field study using high-throughput RNA-sequencing
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[Text file]digest.txt2021-04-26 02:57 414 Text file
[Comma separated]STAGE_YellowPerchRNA_DiffGeneTranscript_EN_FR.csv2021-04-26 02:57 918KComma separated
[Comma separated]STAGE_YellowPerchRNA_WWTP_Parasites_EN_FR.csv2021-04-26 02:57 13KComma separated
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